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Clinical Systems Biology

General Content

Research Highlights From Clinical Systems Biology

  • Sedghamiz H, Chen W, Rice M Jr., Whitley D, Broderick G. Selecting Optimal Models Based on Efficiency and Robustness in Multi-valued Biological Networks, 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE), 2017, 00(0): 200-205.
    (https://www.computer.org/csdl/proceedings/bibe/2017/1324/00/132401a200-abs.html)
  • Craddock TJ, Del Rosario RR, Rice M, Zysman JP, Fletcher MA, Klimas NG, Broderick G. Achieving Remission in Gulf War Illness: A Simulation-Based Approach to Treatment Design. PLoS One. 2015 Jul 20;10(7):e0132774. doi: 10.1371/journal.pone.0132774. eCollection 2015. (https://www.ncbi.nlm.nih.gov/pubmed/26192591)
  • Vashishtha S, Broderick G, Craddock TJ, Fletcher MA, Klimas NG. Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies? PLoS One. 2015 May 18;10(5):e0127364. doi: 10.1371/journal.pone.0127364. eCollection 2015 (https://www.ncbi.nlm.nih.gov/pubmed/25984725)
  • Craddock TJ, Fritsch P, Rice MA Jr, Del Rosario RM, Miller DB, Fletcher MA, Klimas NG, Broderick G. A role for homeostatic drive in the perpetuation of complex chronic illness: gulf war illness and chronic fatigue syndrome. PLoS One. 2014 Jan 8;9(1):e84839. (http://www.ncbi.nlm.nih.gov/pubmed/24416298 )
  • Broderick G, Ben-Hamo R, Vashishtha S, Efroni S, Nathanson L, Barnes Z, Fletcher MA, Klimas N. Altered immune pathway activity under exercise challenge in Gulf War Illness: an exploratory analysis. Brain Behav Immun. 2013 Feb; 28:159-69. (http://www.ncbi.nlm.nih.gov/pubmed/23201588 )
  • Broderick G and Craddock TJA Systems biology of complex symptom profiles: capturing interactivity across behavior, brain and immune regulation. Brain Behav Immun. 2013; 29:1-8. (http://www.ncbi.nlm.nih.gov/pubmed/23022717 )
  • Broderick G et al. A pilot study of immune network remodeling under challenge in Gulf War Illness. Brain Behav Immun. 2011; 25(2): 302-13. (http://www.sciencedirect.com/science/article/pii/S0889159110005179 )
  • Broderick G et al. A formal analysis of cytokine networks in chronic fatigue syndrome. Brain Behav Immun. 2010; 24(7): 1209-1217. (http://www.sciencedirect.com/science/article/pii/S0889159110001017 )